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RNA worlds : from life's origins to diversity in gene regulation / edited by John F. Atkins, Raymond F. Gesteland, Thomas R. Cech. - xv, 361 pages : illustrations (some color) ; 29 cm.

Includes bibliographical references and index.

Foreword to the first edition of The RNA world -- Prologue to the first edition of The RNA world -- The RNA worlds in context -- Setting the stage the history, chemistry, and geobiology behind RNA -- The origins of the RNA world -- Getting past the RNA world the initial Darwinian ancestor -- The origins of cellular life -- Riboswitches and the RNA world -- Riboswitches structures and mechanisms -- Small self-cleaving ribozymes -- Group II introns mobile ribozymes that invade DNA -- The roles of RNA in the synthesis of protein -- Evolution of protein synthesis from an RNA world -- the ribosome some hard facts about its structure and hot air about its evolution -- Noncoding RNPs of viral origin -- Spliceosome structure and function -- Telomerase an RNP enzyme synthesizes DNA -- Bacterial small RNA regulators versatile roles and rapidly evolving variations -- RNA in defense CRISPRs protect prokaryotes against mobile genetic elements -- Ancestral roles of small RNAs an ago-centric perspective -- RNA interference and heterochromatin assembly -- The X as model for RNA's niche in epigenomic regulation -- The long arm of long noncoding RNAs roles as sensors regulating gene transcriptional programs -- Folding and finding RNA secondary structure -- Predicting and modeling RNA architecture -- RNA reactions one molecule at a time -- Aptamers and the RNA world, pat and present -- In vivo RNAi today and tomorrow / Francis Crick / James D. Watson / Thomas R. Cech / Steven A. Benner, Hyo-Joong Kim, Zunyi Yang / Michael P. Robertson, Gerald F. Joyce / Michael Yarus / Jason P. Schrum, Ting F. Zhu, Jack W. Szostak / Ronald R. Breaker / Andrew D. Garst, Andrea L. Edwards, Robert T. Batey / Adrian R. Ferre-D'Amare, William G. Scott / Alan M. Lambowitz, Steven Zimmerly / Peter B. Moore, Thomas A. Steitz / Harry F. Noller / V. Ramakrishnan / Joan Steitz ... [and others] / Cindy L. Will, Reinhard Luhrmann / Elizabeth H. Blackburn, Kathleen Collins / Susan Gottesman, Gisela Storz / Matthijs M. Jore, Stan J.J. Brouns, John van der Oost / Leemor Joshua-Tor, Gregory J. Hannon / Tom Volpe, Robert A. Martienssen / Jeannie T. Lee / Xiangting Wang ... [and others] / David H. Mathews, Walter N. Moss, Douglas H. Turner / Eric Westhof, Benoit Masquida, Fabrice Jossinet / Ignacio Tinoco, Gang Chen, Xiaohui Qu / Larry Gold ... [and others] / Norbert Perrimon, Jian-Quan Ni, Lizabeth Perkins.

ISBN: 9780879699468 0879699469

LCCN: 2010027850

Subjects--Topical Terms:
Genetic regulation.
RNA.
Gene Expression Regulation.

LC Class. No.: QH450 / .R635 2011

Dewey Class. No.:

National Library of Medicine Call No.: QU 58.7 / .R635 2011