Human molecular genetics 2 / Tom Strachan and Andrew P. Read

Includes bibliographical references and indexes

-- DNA structure and gene expression -- Chromosomes in cells -- Genes in pedigrees -- Cell-based DNA cloning -- Nucleic acid hybridization assays -- PCR, DNA sequencing and in vitro mutagenesis -- Organization of the human genome -- Human gene expression -- Instability of the human genome : mutation and DNA repair -- Physical and transcript mapping -- Genetic mapping of mendelian characters -- Genetic mapping of complex characters -- Genome projects -- Our place in the tree of life -- Identifying human disease genes -- Molecular pathology -- Genetic testing in individuals and populations -- Cancer genetics -- Complex diseases : theory and results -- Studying human gene structure, expression and function using cultured cells and cell extracts -- Genetic manipulation of animals -- Gene therapy and other molecular genetic-based therapeutic approaches