TY  - BOOK
AU  - Makowski,Gregory S.
ED  - ebrary, Inc.
TI  - Advances in clinical chemistry
T2  - Advances in clinical chemistry
SN  - 9780120103423
AV  - QY90 .M35 2006
PY  - 2006///
CY  - New York
PB  - Academic Press
KW  - Clinical chemistry
KW  - Biochemistry
N1  - Contents; -- Contributors; -- Preface; -- Chapter 1: Tumor Markers in Detection of Lung Cancer; -- 1. Abstract; -- 2. Introduction; -- 3. Blood/Serum Tumor Markers in the Detection of Lung Cancers; -- 4. Role of Serum Tumor Markers in the Detection of Lung Cancers; -- 5. Role of Other Serum Markers in the Detection of Lung Cancers; -- 6. Role of a Tumor Marker Panel in Improving the Detection of Lung Cancers; -- 7. Value of Less Frequently Used Markers in the Diagnosis of Lung Cancers; -- 8. Summary and Conclusions; -- References; -- Chapter 2: Advances in Serum Protein Electrophoresis; -- 1. Abstract; -- 2. Introduction; -- 3. Technique; -- 4. Instruments; -- 5. Precision; -- 6. Comparison with Gel-Based Techniques; -- 7. Reference Intervals; -- 8. Electrophoretic Patterns; -- 9. Online Processing of Digital Absorbance Data; -- 10. Detection of Monoclonal Proteins; -- 11. Typing of Monoclonal Proteins; -- 12. Urine and Body Fluid Analysis; -- 13. Quality Control; -- 14. Interferences; -- 15. "Open" Capillary Electrophoresis Systems; -- 16. Conclusions; -- Acknowledgment; -- References; -- Chapter 3: Aspirin Resistance: A. Review Of Diagnostic. Methodology, Mechanisms, and Clinical Utility; -- 1. Abstract; -- 2. Introduction; -- 3. Aspirin: Mechanism of Action; -- 4. Methods to Detect Aspirin Resistance; -- 5. Aspirin Resistance Associated with Adverse Outcomes; -- 6. Mechanisms of Aspirin Resistance; -- 7. Aspirin Resistance Associated with Cardiovascular and Cerebrovascular Disease; -- 8. Summary and Recommendations; -- References; -- Chapter 4: Vitreous Fluid Biomarkers; -- 1. Abstract; -- 2. Introduction; -- 3. Methods; -- 4. Molecular Biology; -- 5. Ocular Disease and Clinical Significance; -- 6. Conclusions; -- References; -- Chapter 5: Tumor-associated Carbonic Anhydrases and Their Clinical Significance; -- 1. Abstract; -- 2. Carbonic Anhydrases; -- 3. Basic Characteristics of CA IX and CA XII; -- 4. Regulation of CA IX/CA XII Expression; -- 5. Distribution of CA IX/CA XII in Tumors and Their Clinical Usefulness; -- 6. Role of CA IX/CA XII in Tumor Progression; -- 7. CA IX and CA XII as Molecular Targets for Anticancer Therapy; -- 8. Concluding Remarks; -- Acknowledgments; -- References; -- Chapter 6: Mitochondrial Disease: Maintenance of Mitochondrial Genome and Molecular Diagnostics; -- 1. Abstract; -- 2. Introduction; -- 3. Human Mitochondrial DNA; -- 4. Maintenance of Mitochondrial DNA; -- 5. Pathogenesis of Mitochondrial DNA Mutation; -- 6. Tests of Mitochondrial DNA; -- 7. Mitochondrial DNA in Common Disease; -- 8. Nuclear DNA Mutations and Mitochondrial Disease; -- 9. Perspectives; -- 10. Conclusion and Remarks; -- Acknowledgments; -- References; -- Chapter 7: Microfluidic Enzyme-Linked Immunosorbent Assay Technology; -- 1. Abstract; -- 2. Introduction; -- 3. Key Issues in Develo
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