TY - BOOK AU - Mackness,B. ED - International Conference on Paraoxonases TI - The paraoxonases: their role in disease development and xenobiotic metabolism T2 - Proteins and cell regulation SN - 1402065604 AV - QU136 .I594 2008 PY - 2007/// CY - Dordrecht, London PB - Springer KW - Paraoxonase KW - Congresses KW - Aryldialkylphosphatase N1 - Selected conference papers; Contributors ; Preface ; PART 1 The Bert La Du Memorial Lecture ; Paraoxonases: An Historical Perspective; ; C.E. Furlong; ; PART 2 PONs and Atherosclerosis ; 1. Glucose Inactivates Paraoxonase 1 (PON1) and Displaces it from High Density Lipoprotein (HDL) to a Free PON1 Form; ; Mira Rosenblat, Orly Sapir and Michael Aviram; ; 2. Paraoxonase-1 and Cardiovascular Disease; ; B. Mackness and M.I. Mackness; ; 3. Oxidative Stress and Antioxidants and PON 1 in Health and Disease; ; Eser Yildirim Sozmen, Ferhan Girgin Sagin, Meral Kayikcioglu and Bulent Sozmen; ; 4. D-4F Increases Paraoxonase 1 Activity in HDL; ; Greg Hough; ; 5. Paraoxonase 1 (PON1), A Junction Between the Metabolisms of Homocysteine and Lipids; ; H. Jakubowski; ; 6. The Role of PON2 and PON3 in Atherosclerosis and Related Traits; ; N. Bourquard, D.M. Shih, C.J. Ng, N. Villa-Garcia, K. Nakamura, D.A. Stoltz, E. Ozer, V. Grijalva, N. Rozengurt, S. Y. Hama, J. Zabner, M. Navab, A.M. Fogelman and S.T. Reddy; ; 7. Paraoxonase 1 and Postprandial Lipemia; ; A. Alipour, B. Coll, A.P. Rietveld, Marsillach, J. Camps, J. Joven, J.W.F. Elte and M. Castro Cabezas; ; 8. PON1 Genotypes and Coronary Heart Disease; ; M. Roest and H.A.M. Voorbij; ; PART 3 PON1 Structure ; 9. Human Paraoxonase I: A Potential Bioscavenger of Organophosphorus Nerve Agents; ; David T. Yeung, David E. Lenz and Douglas M. Cerasoli; ; 10. Stabilisation of Active Form of Natural Human PON1 Requires HPBP; ; D. Rochu, E. Chabriere, M. Elias, F. Renault, C. Clery-Barraud and P. Masson; ; PART 4 PONs in Disease other than Atherosclerosis ; 11. Paraoxonase-1 in Chronic Liver Diseases, Neurological Diseases and HIV Infection; ; J. Marsillach, S. Parra, N. Ferre, B. Coll, C. Alonso-Villaverde, J. Joven and J. Camps; ; 12. Age-Related Alterations in PON1; ; I. Seres, T. Fulop, G. Paragh and A. Khalil; ; PART 5 PON and Toxicology ; 13. Paraoxonase (PON1) and Organophosphate Toxicity; ; L.G. Costa, T.B. Cole, K.L. Jansen and C.E. Furlong; ; 14. Implications of Paraoxonase-1 (PON1) Activity and Polymorphisms on Biochemical and Clinical Outcomes in Workers Exposed to Pesticides; ; A.F. Hernández, O. López, G. Pena, J.L. Serrano, T. Parrón, L. Rodrigo, F. Gil and A. Pla; ; PART 6 PON-Genetics and Regulation ; 15. Transcriptional Regulation of the Paraoxonase Genes; ; S. P. Deakin and R. W. James; ; 16. Effect of Lipid Lowering Medications on PON 1; ; G. Paragh, M. Harangi and L Seres; ; 17. The Functional Consequences of Polymorphisms in the Human PON1 Gene; ; C.E. Furlong, R.J Richter, W.-F. Li, V.H. Brophy, C. Carlson, M. Rieder, D. Nickerson, L.G. Costa, J. Ranchalis, A.J. Lusis, D.M. Shih, A. Tward and G.P. Jarvik; ; 18. Dietary Modulation of Paraoxonase-1 Activity and Concentration in Humans; ; C. Dalgård; ; PART 7 PONs Biochemistry ; 19. PONs' Natural Substrates – The Key for their Physiological Roles; ; D.I. Draganov and J.F. Teiber; ; 20. Paraoxonases, Quorum Sensing, and Pseudomonas aeruginosa; ; D.A. Stoltz, E.A. Ozer and J. Zabner; ; Index N2 - Features a distillation of the plenary lectures presented at the International Conference on Paraoxonases, held in Hajduszoboszlo, Hungary, in September 2006. This book offers a review of paraoxonase research ER -