TY - BOOK AU - Goodman,Louis S. AU - Hardman,Joel G AU - Limbird,Lee E AU - Gilman,Alfred Goodman TI - Goodman and Gilman's the pharmacological basis of therapeutics SN - 0071354697 AV - RM300 .G644 2001 PY - 2001///] CY - New York PB - McGraw-Hill Medical Pub. Division KW - Pharmacology KW - Chemotherapy KW - Drug Therapy N1 - Includes bibliographical references and index; Contents; Sect. I General Principles; Introduction; / Alfred Goodman Gilman; 1 Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, and Elimination; / Grant R. Wilkinson; 2 Pharmacodynamics: Mechanisms of Drug Action and the Relationship Between Drug Concentration and Effect; / Elliott M. Ross, Terry P. Kenakin; 3 Principles of Therapeutics; / Alan S. Nies; 4 Principles of Toxicology and Treatment of Poisoning; / Curtis D. Klaassen; 5 Gene Therapy; / Christopher S. Rogers, Bruce A. Sullenger, Alfred L. George, Jr; Sect. II Drugs Acting at Synaptic and Neuroeffector Junctional Sites; 6 Neurotransmission: The Autonomic and Somatic Motor Nervous Systems; / Brian B. Hoffman, Palmer Taylor; 7 Muscarinic Receptor Agonists and Antagonists; / Joan Heller Brown, Palmer Taylor; 8 Anticholinesterase Agents; / Palmer Taylor; 9 Agents Acting at the Neuromuscular Junction and Autonomic Ganglia; / Palmer Taylor; 10 Catecholamines, Sympathomimetic Drugs, and Adrenergic Receptor Antagonists; / Brian B. Hoffman; 11 5-Hydroxytryptamine (Serotonin): Receptor Agonists and Antagonists; / Elaine Sanders-Bush, Steven E. Mayer; Sect. III Drugs Acting on the Central Nervous System; 12 Neurotransmission and the Central Nervous System; / Floyd E. Bloom; 13 History and Principles of Anesthesiology; / Charles Beattie; 14 General Anesthetics; / Alex S. Evers, C. Michael Crowder; 15 Local Anesthetics; / William A. Catterall, Kenneth Mackie; 16 Therapeutic Gases: Oxygen, Carbon Dioxide, Nitric Oxide, and Helium; / Eric J. Moody, Brett A. Simon, Roger A. Johns; 17 Hypnotics and Sedatives; / Dennis S. Charney, S. John Mihic, R. Adron Harris; 18 Ethanol; / Michael F. Fleming, S. John Mihic, R. Adron Harris; 19 Drugs and the Treatment of Psychiatric Disorders: Depression and Anxiety Disorders; / Ross J. Baldessarini; 20 Drugs and the Treatment of Psychiatric Disorders: Psychosis and Mania; / Ross J. Baldessarini, Frank I. Tarazi; 21 Drugs Effective in the Therapy of the Epilepsies; / James O. McNamara; 22 Treatment of Central Nervous System Degenerative Disorders; / David G. Standaert, Anne B. Young; 23 Opioid Analgesics; / Howard B. Gutstein, Huda Akil; 24 Drug Addiction and Drug Abuse; / Charles P. O'Brien; Sect. IV Autacoids; Drug Therapy of Inflammation; Introduction; / Jason D. Morrow, L. Jackson Roberts II; 25 Histamine, Bradykinin, and their Antagonists; / Nancy J. Brown, L. Jackson Roberts II; 26 Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor; / Jason D. Morrow, L. Jackson Roberts II; 27 Analgesic-Antipyretic and Antiinflammatory Agents and Drugs Employed in the Treatment of Gout; / L. Jackson Roberts II, Jason D. Morrow; 28 Drugs Used in the Treatment of Asthma; / Bradley J. Undem, Lawrence M. Lichtenstein; Sect. V Drugs Affecting Renal and Cardiovascular Function; 29 Diuretics; / Edwin K. Jackson; 30 Vasopressin and Other Agents Affecting the Renal Conservation of Water; / Edwin K. Jackson; 31 Renin and Angiotensin; / Edwin K. Jackson; 32 Drugs Used for the Treatment of Myocardial Ischemia; / David M. Kerins, Rose Marie Robertson, David Robertson; 33 Antihypertensive Agents and the Drug Therapy of Hypertension; / John A. Oates, Nancy J. Brown; 34 Pharmacological Treatment of Heart Failure; / Henry Ooi, Wilson Colucci; 35 Antiarrhythmic Drugs; / Dan M. Roden; 36 Drug Therapy for Hypercholesterolemia and Dyslipidemia; / Robert W. Mahley, Thomas P. Bersot; Sect. VI Drugs Affecting Gastrointestinal Function; 37 Agents Used for Control of Gastric Acidity and Treatment of Peptic Ulcers and Gastroesophageal Reflux Disease; / Willemijntje A. Hoogerwerf, Pankaj J. Pasricha; 38 Prokinetic Agents, Antiemetics, and Agents Used in Irritable Bowel Syndrome; / Pankaj J. Pasricha; 39 Agents Used for Diarrhea, Constipation, and Inflammatory Bowel Disease; Agents Used for Biliary and Pancreatic Disease; / Syed Jafri, Pankaj J. Pasricha; Sect. VII Chemotherapy of Parasitic Infections; Introduction; / James W. Tracy, Leslie T. Webster, Jr; 40 Drugs Used in the Chemotherapy of Protozoal Infections: Malaria; / James W. Tracy, Leslie T. Webster, Jr; 41 Drugs Used in the Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections; / James W. Tracy, Leslie T. Webster, Jr; 42 Drugs Used in the Chemotherapy of Helminthiasis; / James W. Tracy, Leslie T. Webster, Jr; Sect. VIII Chemotherapy of Microbial Diseases; 43 Antimicrobial Agents: General Considerations; / Henry F. Chambers; 44 Antimicrobial Agents: Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections; / William A. Petri, Jr; 45 Antimicrobial Agents: Penicillins, Cephalosporins, and Other [beta]-Lactam Antibiotics; / William A. Petri, Jr; 46 Antimicrobial Agents: The Aminoglycosides; / Henry F. Chambers; 47 Antimicrobial Agents: Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents; / Henry F. Chambers; 48 Antimicrobial Agents: Drugs Used in the Chemotherapy of Tuberculosis, Mycobacterium avium Complex Disease, and Leprosy; / William A. Petri, Jr; 49 Antimicrobial Agents: Antifungal Agents; / John E. Bennett; 50 Antimicrobial Agents: Antiviral Agents (Nonretroviral); / Frederick G. Hayden; 51 Antimicrobial Agents: Antiretroviral Agents; / Stephen P. Raffanti, David W. Haas; Sect. IX Chemotherapy of Neoplastic Diseases; Introduction; / Paul Calabresi, Bruce A. Chabner; 52 Antineoplastic Agents [and others]; / Bruce A. Chabner, David P. Ryan, Luis Paz-Ares; Sect. X Drugs Used for Immunomodulation; 53 Immunomodulators: Immunosuppressive Agents, Tolerogens, and Immunostimulants; / Alan M. Krensky, Terry B. Strom, Jaffrey A. Bluestone; Sect. XI Drugs Acting on the Blood and the Blood-Forming Organs; 54 Hematopoietic Agents: Growth Factors, Minerals, and Vitamins; / Robert S. Hillman; 55 Anticoagulant, Thrombolytic, and Antiplatelet Drugs; / Philip W. Majerus, Douglas M. Tollefsen; Sect. XII Hormones and Hormone Antagonists; 56 Pituitary Hormones and Their Hypothalamic Releasing Factors; / Keith L. Parker, Bernard P. Schimmer; 57 Thyroid and Antithyroid Drugs; / Alan P. Farwell, Lewis E. Braverman; 58 Estrogens and Progestins; / David S. Loose-Mitchell, George M. Stancel; 59 Androgens; / Peter J. Snyder; 60 Adrenocorticotropic Hormone; Adrenocortical Steroids and Their Synthetic Analogs; Inhibitors of the Synthesis and Actions of Adrenocortical Hormones; / Bernard P. Schimmer, Keith L. Parker; 61 Insulin, Oral Hypoglycemic Agents, and the Pharmacology of the Endocrine Pancreas; / Stephan N. Davis, Daryl K. Granner; 62 Agents Affecting Calcification and Bone Turnover: Calcium, Phosphate, Parathyroid Hormone, Vitamin D, Calcitonin, and Other Compounds; / Robert Marcus; Sect. XIII The Vitamins; Introduction; / Robert Marcus, Ann M. Coulston; 63 Water-Soluble Vitamins: The Vitamin B Complex and Ascorbic Acid; / Robert Marcus, Ann M. Coulston; 64 Fat-Soluble Vitamins: Vitamins A, K, and E; / Robert Marcus, Ann M. Coulston; Sect. XIV Dermatology; 65 Dermatological Pharmacology; / Eric L. Wyatt, Steven H. Sutter, Lynn A. Drake; Sect. XV Ophthalmology; 66 Ocular Pharmacology; / Sayoko E. Moroi, Paul R. Lichter; Sect. XVI Toxicology; 67 Heavy Metals and Heavy-Metals Antagonists; / Curtis D. Klaassen; 68 Nonmetallic Environmental Toxicants: Air Pollutants, Solvents and Vapors, and Pesticides; / Curtis D. Klaassen; App. I Principles of Prescription Order Writing and Patient Compliance; / Lauralea Edwards, Dan M. Roden; App. II Design and Optimization of Dosage Regimens: Pharmacokinetic Data; / Kenneth E. Thummel, Danny D. Shen; Index ER -