TY - BOOK AU - Atkins,John F. AU - Gesteland,Raymond F. AU - Cech,Thomas TI - RNA worlds: from life's origins to diversity in gene regulation SN - 9780879699468 AV - QH450 .R635 2011 PY - 2011///] CY - Cold Spring Harbor, N.Y. PB - Cold Spring Harbor Laboratory Press KW - Genetic regulation KW - RNA KW - Gene Expression Regulation N1 - Includes bibliographical references and index; Foreword to the first edition of The RNA world; / Francis Crick; -- Prologue to the first edition of The RNA world; / James D. Watson; -- The RNA worlds in context; / Thomas R. Cech; -- Setting the stage; the history, chemistry, and geobiology behind RNA; / Steven A. Benner, Hyo-Joong Kim, Zunyi Yang; -- The origins of the RNA world; / Michael P. Robertson, Gerald F. Joyce; -- Getting past the RNA world; the initial Darwinian ancestor; / Michael Yarus; -- The origins of cellular life; / Jason P. Schrum, Ting F. Zhu, Jack W. Szostak; -- Riboswitches and the RNA world; / Ronald R. Breaker; -- Riboswitches; structures and mechanisms; / Andrew D. Garst, Andrea L. Edwards, Robert T. Batey; -- Small self-cleaving ribozymes; / Adrian R. Ferr{acute}e-D'Amar{acute}e, William G. Scott; -- Group II introns; mobile ribozymes that invade DNA; / Alan M. Lambowitz, Steven Zimmerly; -- The roles of RNA in the synthesis of protein; / Peter B. Moore, Thomas A. Steitz; -- Evolution of protein synthesis from an RNA world; / Harry F. Noller; -- the ribosome; some hard facts about its structure and hot air about its evolution; / V. Ramakrishnan; -- Noncoding RNPs of viral origin; / Joan Steitz ... [and others]; -- Spliceosome structure and function; / Cindy L. Will, Reinhard L{uml}uhrmann; -- Telomerase; an RNP enzyme synthesizes DNA; / Elizabeth H. Blackburn, Kathleen Collins; -- Bacterial small RNA regulators; versatile roles and rapidly evolving variations; / Susan Gottesman, Gisela Storz; -- RNA in defense; CRISPRs protect prokaryotes against mobile genetic elements; / Matthijs M. Jore, Stan J.J. Brouns, John van der Oost; -- Ancestral roles of small RNAs; an ago-centric perspective; / Leemor Joshua-Tor, Gregory J. Hannon; -- RNA interference and heterochromatin assembly; / Tom Volpe, Robert A. Martienssen; -- The X as model for RNA's niche in epigenomic regulation; / Jeannie T. Lee; -- The long arm of long noncoding RNAs; roles as sensors regulating gene transcriptional programs; / Xiangting Wang ... [and others]; -- Folding and finding RNA secondary structure; / David H. Mathews, Walter N. Moss, Douglas H. Turner; -- Predicting and modeling RNA architecture; / Eric Westhof, Beno{circ}it Masquida, Fabrice Jossinet; -- RNA reactions one molecule at a time; / Ignacio Tinoco, Gang Chen, Xiaohui Qu; -- Aptamers and the RNA world, pat and present; / Larry Gold ... [and others]; -- In vivo RNAi; today and tomorrow; / Norbert Perrimon, Jian-Quan Ni, Lizabeth Perkins ER -