000			03786cam a2200313 i 4500
008			970612s1998 caua b 001 0 eng
020			_a0125503601 _q(alk. paper)
020			_a9780125503600 _q(alk. paper)
035			_a(OCoLC)37179642 _z(OCoLC)38425672 _z(OCoLC)40802225 _z(OCoLC)314805542 _z(OCoLC)317783710
040			_aDLC _beng _cDLC _dMMU _dUKM _dBAKER _dNLGGC _dBTCTA _dYDXCP _dOCLCG _dZWZ _dDEBBG _dOCLCQ _dI8M _dOCLCO _dUA@ _dOCLCQ _dUtOrBLW _dBAUN _erda
049			_aBAUN_MERKEZ
050	0	4	_aQD321 _b.G97 1998
082	0	0	_221
100	1		_aGyörgydeák, Zoltán _989040 _eaut
245	1	0	_aMonosaccharide sugars : _bchemical synthesis by chain elongation, degradation, and epimerization / _cZoltán Györgydeák, István F. Pelyvás
264		1	_aSan Diego : _bAcademic Press, _c1998
300			_axviii, 508 pages : _billustrations ; _c24 cm
336			_2rdacontent _atext _btxt
337			_2rdamedia _aunmediated _bn
338			_2rdacarrier _avolume _bnc
504			_aIncludes bibliographical references and index
505	0	0	_tAscending Synthesis of Monosaccharides: Building up with Total Synthesis. _tBuilding up of Sugars with Ascending Synthesis. _tChain Extension with Diazoalkanes. _tChain Extension with Malonester Derivatives. _tChain Extensions with Phosphoranes. _tOlefination Reactions for the Synthesis of Chain-Extended Monosaccharides. _tMiscellaneous Methods for Chain Extension of the Monosaccharide Chain. _t-- Descending Synthesis of Monosaccharides: The Disulfone-Degradation. _tDegradation of the Calcium Salts of Aldonic Acids with Hydrogen Peroxide. _tDescending of Acylated Aldononitriles. _tDegradation of Saccharides with Oxidative Methods. _tDegradation of the Peroxide Derivatives of Saccharides. _tChain Shortening of Saccharides by Means of Photochemical Methods. _t-- Preparation of Sugars with Isomerization: Epimerization of Saccharides in Alkaline Medium. _tEpimerization of Sugars with Molybdate Ions. _tEpimerization of Saccharides with the Amine-Complexes of Transition and Alkalialine Earth Metals. _t-- Subject Index
520			_aIn a single volume, Monosaccharide Sugars critically summarizes the applied and potentially useful strategies for the synthesis and degradation of monosaccharides by chain-elongation, degradation, and epimerization. These methodologies permit the synthesis of rare or unnatural monosaccharides that are frequently employed as chiral building blocks in natural products synthesis, as well as for producing sugar derivatives labeled with radioactive isotopes. Representative and well-established experimental procedures are provided to illustrate the potential of the synthetic transformation. Degradation of carbohydrates also represents an invaluable tool for the structural elucidation of certain natural products, suchas glycosides, antibiotics, and polysaccharides. When describing the individual methods, unique supplementary collections of the prepared sugar derivatives are shown in tabular form. This compendium will eliminate tedious literature searches for those engaged in research and teaching on the chemistry and biochemistry of saccharides and other natural products, and also for those working on the medicinal and metabolic investigation of related substances of biological importance. Key Features * Illustrates the practical potential of well-established experimental procedures in synthetic transformations * Provides supplementary collections of prepared sugar derivatives in tabular form * Summarizes in a single volume the methods of obtaining carbohydrate-derived compounds
650		0	_aMonosaccharides _xSynthesis _9104003
650		0	_aMonosaccharides _xchemical synthesis _9104002
700	1		_aPelyvás, I. F. _q(István F.), _d1947- _993128 _eaut
900			_a3789
942			_2lcc _cKT
999			_c3619 _d3619