000			02703nam a2200397 i 4500
008			970107s1996 nyua b 001 0 eng d
010			_a97116881
020			_a0879694858
035			_a(OCoLC)
040			_aNcWsW-M _cDLC _dNBG _dMMU _dCUY _dSQU _dDAY _dBAUN _erda _beng
049			_aBAUN_MERKEZ
050	0	0	_aRC268.4 _b.G4465 1996
060	0	4	_aQZ202 _b.G32 1996
082	0	0	_221
245	0	0	_aGenetic instability in cancer / _cguest editor, T. Lindahl
264		1	_aPlainview, NY : _bCold Spring Harbor Laboratory Press, _c1996.
300			_avi, 353 pages : _billustrations ; _c26 cm
336			_2rdacontent _atext _btxt
337			_2rdamedia _aunmediated _bn
338			_2rdacarrier _avolume _bnc
490	1		_aCancer surveys, _x0261-2429 ; _vv. 28
500			_a"Published for the Imperial Cancer Research Fund."
504			_aIncludes bibliographical references and index
505	0		_tIntroduction _t-- DNA synthesis errors, mutators and cancer _t-- DNA polymerase and the control of DNA damage induced mutagenesis in eukaryotes _t-- Patterns of mutation in cancer cells _t-- Mismatch repair and cancer _t-- Genomic instability and tolerance to alkylating agents _t-- The relationship of DNA methylation to cancer _t-- Neoplastic transformation: the contrasting stability of human and mouse cells _t-- Damage inducible mutagenesis: recent insights into the activities of the Umu family of mutagenesis proteins _t-- The relevance of bacterial mutators to understanding human cancer _t-- Mutation in resting cells: the role of endogenous DNA damage _t-- TP53 tumour suppressor gene: clues to molecular carcinogenesi and cancer therapy _t-- Telomere maintenance in tumour cells _t-- Regulation of genomic instability in preneoplastic cells _t-- Chromosome abnormalities in leukemia: the 11q23 paradigm _t-- Clonal chromosome abnormalities in neoplastic cells: evidence of genetic instability? _t-- DNA damage detection by DNA dependent protein kinase and related enzymes _t-- Mammalian X ray sensitive mutants: a tool for the elucidation of the cellular response to ionizing radiation _t-- Mechanism of V(D)J recombination _t-- Transrearrangements as biomarkers for risk of lymphoid malignancy _t-- Many mutations in cancers
650		0	_aCancer _xGenetic aspects _9103640
650		0	_aDNA repair _9103641
650		0	_aChromosome abnormalities _9103642
650		2	_aNeoplasms _xgenetics _9103643
650		0	_aDNA repair _9103641
650		0	_aChromosome Aberrations _9103644
700	1		_aLindahl, T. _q(Tomas), _d1938- _989422 _eaut
710	2		_aImperial Cancer Research Fund (Great Britain) _9103645
830		0	_9103646 _aCancer surveys ; _vvolume 28.
900			_a2519
942			_2lcc _cKT
999			_c3900 _d3900