Goodman and Gilman's the pharmacological basis of therapeutics
Goodman and Gilman's the pharmacological basis of therapeutics
Goodman and Gilman's the pharmacological basis of therapeutics Pharmacological basis of therapeutics
- 10th ed. / editors, Joel G. Hardman, Lee E. Limbird ; consulting editor Alfred Goodman Gilman
- xxvii, 2,148 pages, [1] folded leaf of plate : illustrations (some color) ; 26 cm
Includes bibliographical references and index
Contents Sect. I General Principles Introduction 1 Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, and Elimination 2 Pharmacodynamics: Mechanisms of Drug Action and the Relationship Between Drug Concentration and Effect 3 Principles of Therapeutics 4 Principles of Toxicology and Treatment of Poisoning 5 Gene Therapy Sect. II Drugs Acting at Synaptic and Neuroeffector Junctional Sites 6 Neurotransmission: The Autonomic and Somatic Motor Nervous Systems 7 Muscarinic Receptor Agonists and Antagonists 8 Anticholinesterase Agents 9 Agents Acting at the Neuromuscular Junction and Autonomic Ganglia 10 Catecholamines, Sympathomimetic Drugs, and Adrenergic Receptor Antagonists 11 5-Hydroxytryptamine (Serotonin): Receptor Agonists and Antagonists Sect. III Drugs Acting on the Central Nervous System 12 Neurotransmission and the Central Nervous System 13 History and Principles of Anesthesiology 14 General Anesthetics 15 Local Anesthetics 16 Therapeutic Gases: Oxygen, Carbon Dioxide, Nitric Oxide, and Helium 17 Hypnotics and Sedatives 18 Ethanol 19 Drugs and the Treatment of Psychiatric Disorders: Depression and Anxiety Disorders 20 Drugs and the Treatment of Psychiatric Disorders: Psychosis and Mania 21 Drugs Effective in the Therapy of the Epilepsies 22 Treatment of Central Nervous System Degenerative Disorders 23 Opioid Analgesics 24 Drug Addiction and Drug Abuse Sect. IV Autacoids; Drug Therapy of Inflammation Introduction 25 Histamine, Bradykinin, and their Antagonists 26 Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor 27 Analgesic-Antipyretic and Antiinflammatory Agents and Drugs Employed in the Treatment of Gout 28 Drugs Used in the Treatment of Asthma Sect. V Drugs Affecting Renal and Cardiovascular Function 29 Diuretics 30 Vasopressin and Other Agents Affecting the Renal Conservation of Water 31 Renin and Angiotensin 32 Drugs Used for the Treatment of Myocardial Ischemia 33 Antihypertensive Agents and the Drug Therapy of Hypertension 34 Pharmacological Treatment of Heart Failure 35 Antiarrhythmic Drugs 36 Drug Therapy for Hypercholesterolemia and Dyslipidemia Sect. VI Drugs Affecting Gastrointestinal Function 37 Agents Used for Control of Gastric Acidity and Treatment of Peptic Ulcers and Gastroesophageal Reflux Disease 38 Prokinetic Agents, Antiemetics, and Agents Used in Irritable Bowel Syndrome 39 Agents Used for Diarrhea, Constipation, and Inflammatory Bowel Disease; Agents Used for Biliary and Pancreatic Disease Sect. VII Chemotherapy of Parasitic Infections Introduction 40 Drugs Used in the Chemotherapy of Protozoal Infections: Malaria 41 Drugs Used in the Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections 42 Drugs Used in the Chemotherapy of Helminthiasis Sect. VIII Chemotherapy of Microbial Diseases 43 Antimicrobial Agents: General Considerations 44 Antimicrobial Agents: Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections 45 Antimicrobial Agents: Penicillins, Cephalosporins, and Other [beta]-Lactam Antibiotics 46 Antimicrobial Agents: The Aminoglycosides 47 Antimicrobial Agents: Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents 48 Antimicrobial Agents: Drugs Used in the Chemotherapy of Tuberculosis, Mycobacterium avium Complex Disease, and Leprosy 49 Antimicrobial Agents: Antifungal Agents 50 Antimicrobial Agents: Antiviral Agents (Nonretroviral) 51 Antimicrobial Agents: Antiretroviral Agents Sect. IX Chemotherapy of Neoplastic Diseases Introduction 52 Antineoplastic Agents [and others] Sect. X Drugs Used for Immunomodulation 53 Immunomodulators: Immunosuppressive Agents, Tolerogens, and Immunostimulants Sect. XI Drugs Acting on the Blood and the Blood-Forming Organs 54 Hematopoietic Agents: Growth Factors, Minerals, and Vitamins 55 Anticoagulant, Thrombolytic, and Antiplatelet Drugs Sect. XII Hormones and Hormone Antagonists 56 Pituitary Hormones and Their Hypothalamic Releasing Factors 57 Thyroid and Antithyroid Drugs 58 Estrogens and Progestins 59 Androgens 60 Adrenocorticotropic Hormone; Adrenocortical Steroids and Their Synthetic Analogs; Inhibitors of the Synthesis and Actions of Adrenocortical Hormones 61 Insulin, Oral Hypoglycemic Agents, and the Pharmacology of the Endocrine Pancreas 62 Agents Affecting Calcification and Bone Turnover: Calcium, Phosphate, Parathyroid Hormone, Vitamin D, Calcitonin, and Other Compounds Sect. XIII The Vitamins Introduction 63 Water-Soluble Vitamins: The Vitamin B Complex and Ascorbic Acid 64 Fat-Soluble Vitamins: Vitamins A, K, and E Sect. XIV Dermatology 65 Dermatological Pharmacology Sect. XV Ophthalmology 66 Ocular Pharmacology Sect. XVI Toxicology 67 Heavy Metals and Heavy-Metals Antagonists 68 Nonmetallic Environmental Toxicants: Air Pollutants, Solvents and Vapors, and Pesticides App. I Principles of Prescription Order Writing and Patient Compliance App. II Design and Optimization of Dosage Regimens: Pharmacokinetic Data Index / Alfred Goodman Gilman / Grant R. Wilkinson / Elliott M. Ross, Terry P. Kenakin / Alan S. Nies / Curtis D. Klaassen / Christopher S. Rogers, Bruce A. Sullenger, Alfred L. George, Jr. / Brian B. Hoffman, Palmer Taylor / Joan Heller Brown, Palmer Taylor / Palmer Taylor / Palmer Taylor / Brian B. Hoffman / Elaine Sanders-Bush, Steven E. Mayer / Floyd E. Bloom / Charles Beattie / Alex S. Evers, C. Michael Crowder / William A. Catterall, Kenneth Mackie / Eric J. Moody, Brett A. Simon, Roger A. Johns / Dennis S. Charney, S. John Mihic, R. Adron Harris / Michael F. Fleming, S. John Mihic, R. Adron Harris / Ross J. Baldessarini / Ross J. Baldessarini, Frank I. Tarazi / James O. McNamara / David G. Standaert, Anne B. Young / Howard B. Gutstein, Huda Akil / Charles P. O'Brien / Jason D. Morrow, L. Jackson Roberts II / Nancy J. Brown, L. Jackson Roberts II / Jason D. Morrow, L. Jackson Roberts II / L. Jackson Roberts II, Jason D. Morrow / Bradley J. Undem, Lawrence M. Lichtenstein / Edwin K. Jackson / Edwin K. Jackson / Edwin K. Jackson / David M. Kerins, Rose Marie Robertson, David Robertson / John A. Oates, Nancy J. Brown / Henry Ooi, Wilson Colucci / Dan M. Roden / Robert W. Mahley, Thomas P. Bersot / Willemijntje A. Hoogerwerf, Pankaj J. Pasricha / Pankaj J. Pasricha / Syed Jafri, Pankaj J. Pasricha / James W. Tracy, Leslie T. Webster, Jr. / James W. Tracy, Leslie T. Webster, Jr. / James W. Tracy, Leslie T. Webster, Jr. / James W. Tracy, Leslie T. Webster, Jr. / Henry F. Chambers / William A. Petri, Jr. / William A. Petri, Jr. / Henry F. Chambers / Henry F. Chambers / William A. Petri, Jr. / John E. Bennett / Frederick G. Hayden / Stephen P. Raffanti, David W. Haas / Paul Calabresi, Bruce A. Chabner / Bruce A. Chabner, David P. Ryan, Luis Paz-Ares / Alan M. Krensky, Terry B. Strom, Jaffrey A. Bluestone / Robert S. Hillman / Philip W. Majerus, Douglas M. Tollefsen / Keith L. Parker, Bernard P. Schimmer / Alan P. Farwell, Lewis E. Braverman / David S. Loose-Mitchell, George M. Stancel / Peter J. Snyder / Bernard P. Schimmer, Keith L. Parker / Stephan N. Davis, Daryl K. Granner / Robert Marcus / Robert Marcus, Ann M. Coulston / Robert Marcus, Ann M. Coulston / Robert Marcus, Ann M. Coulston / Eric L. Wyatt, Steven H. Sutter, Lynn A. Drake / Sayoko E. Moroi, Paul R. Lichter / Curtis D. Klaassen / Curtis D. Klaassen / Lauralea Edwards, Dan M. Roden / Kenneth E. Thummel, Danny D. Shen
0071354697
2001030728
Pharmacology
Chemotherapy
Pharmacology
Drug Therapy
RM300 / .G644 2001
QV 4 / .G6532 2001
Includes bibliographical references and index
Contents Sect. I General Principles Introduction 1 Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, and Elimination 2 Pharmacodynamics: Mechanisms of Drug Action and the Relationship Between Drug Concentration and Effect 3 Principles of Therapeutics 4 Principles of Toxicology and Treatment of Poisoning 5 Gene Therapy Sect. II Drugs Acting at Synaptic and Neuroeffector Junctional Sites 6 Neurotransmission: The Autonomic and Somatic Motor Nervous Systems 7 Muscarinic Receptor Agonists and Antagonists 8 Anticholinesterase Agents 9 Agents Acting at the Neuromuscular Junction and Autonomic Ganglia 10 Catecholamines, Sympathomimetic Drugs, and Adrenergic Receptor Antagonists 11 5-Hydroxytryptamine (Serotonin): Receptor Agonists and Antagonists Sect. III Drugs Acting on the Central Nervous System 12 Neurotransmission and the Central Nervous System 13 History and Principles of Anesthesiology 14 General Anesthetics 15 Local Anesthetics 16 Therapeutic Gases: Oxygen, Carbon Dioxide, Nitric Oxide, and Helium 17 Hypnotics and Sedatives 18 Ethanol 19 Drugs and the Treatment of Psychiatric Disorders: Depression and Anxiety Disorders 20 Drugs and the Treatment of Psychiatric Disorders: Psychosis and Mania 21 Drugs Effective in the Therapy of the Epilepsies 22 Treatment of Central Nervous System Degenerative Disorders 23 Opioid Analgesics 24 Drug Addiction and Drug Abuse Sect. IV Autacoids; Drug Therapy of Inflammation Introduction 25 Histamine, Bradykinin, and their Antagonists 26 Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor 27 Analgesic-Antipyretic and Antiinflammatory Agents and Drugs Employed in the Treatment of Gout 28 Drugs Used in the Treatment of Asthma Sect. V Drugs Affecting Renal and Cardiovascular Function 29 Diuretics 30 Vasopressin and Other Agents Affecting the Renal Conservation of Water 31 Renin and Angiotensin 32 Drugs Used for the Treatment of Myocardial Ischemia 33 Antihypertensive Agents and the Drug Therapy of Hypertension 34 Pharmacological Treatment of Heart Failure 35 Antiarrhythmic Drugs 36 Drug Therapy for Hypercholesterolemia and Dyslipidemia Sect. VI Drugs Affecting Gastrointestinal Function 37 Agents Used for Control of Gastric Acidity and Treatment of Peptic Ulcers and Gastroesophageal Reflux Disease 38 Prokinetic Agents, Antiemetics, and Agents Used in Irritable Bowel Syndrome 39 Agents Used for Diarrhea, Constipation, and Inflammatory Bowel Disease; Agents Used for Biliary and Pancreatic Disease Sect. VII Chemotherapy of Parasitic Infections Introduction 40 Drugs Used in the Chemotherapy of Protozoal Infections: Malaria 41 Drugs Used in the Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections 42 Drugs Used in the Chemotherapy of Helminthiasis Sect. VIII Chemotherapy of Microbial Diseases 43 Antimicrobial Agents: General Considerations 44 Antimicrobial Agents: Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections 45 Antimicrobial Agents: Penicillins, Cephalosporins, and Other [beta]-Lactam Antibiotics 46 Antimicrobial Agents: The Aminoglycosides 47 Antimicrobial Agents: Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents 48 Antimicrobial Agents: Drugs Used in the Chemotherapy of Tuberculosis, Mycobacterium avium Complex Disease, and Leprosy 49 Antimicrobial Agents: Antifungal Agents 50 Antimicrobial Agents: Antiviral Agents (Nonretroviral) 51 Antimicrobial Agents: Antiretroviral Agents Sect. IX Chemotherapy of Neoplastic Diseases Introduction 52 Antineoplastic Agents [and others] Sect. X Drugs Used for Immunomodulation 53 Immunomodulators: Immunosuppressive Agents, Tolerogens, and Immunostimulants Sect. XI Drugs Acting on the Blood and the Blood-Forming Organs 54 Hematopoietic Agents: Growth Factors, Minerals, and Vitamins 55 Anticoagulant, Thrombolytic, and Antiplatelet Drugs Sect. XII Hormones and Hormone Antagonists 56 Pituitary Hormones and Their Hypothalamic Releasing Factors 57 Thyroid and Antithyroid Drugs 58 Estrogens and Progestins 59 Androgens 60 Adrenocorticotropic Hormone; Adrenocortical Steroids and Their Synthetic Analogs; Inhibitors of the Synthesis and Actions of Adrenocortical Hormones 61 Insulin, Oral Hypoglycemic Agents, and the Pharmacology of the Endocrine Pancreas 62 Agents Affecting Calcification and Bone Turnover: Calcium, Phosphate, Parathyroid Hormone, Vitamin D, Calcitonin, and Other Compounds Sect. XIII The Vitamins Introduction 63 Water-Soluble Vitamins: The Vitamin B Complex and Ascorbic Acid 64 Fat-Soluble Vitamins: Vitamins A, K, and E Sect. XIV Dermatology 65 Dermatological Pharmacology Sect. XV Ophthalmology 66 Ocular Pharmacology Sect. XVI Toxicology 67 Heavy Metals and Heavy-Metals Antagonists 68 Nonmetallic Environmental Toxicants: Air Pollutants, Solvents and Vapors, and Pesticides App. I Principles of Prescription Order Writing and Patient Compliance App. II Design and Optimization of Dosage Regimens: Pharmacokinetic Data Index / Alfred Goodman Gilman / Grant R. Wilkinson / Elliott M. Ross, Terry P. Kenakin / Alan S. Nies / Curtis D. Klaassen / Christopher S. Rogers, Bruce A. Sullenger, Alfred L. George, Jr. / Brian B. Hoffman, Palmer Taylor / Joan Heller Brown, Palmer Taylor / Palmer Taylor / Palmer Taylor / Brian B. Hoffman / Elaine Sanders-Bush, Steven E. Mayer / Floyd E. Bloom / Charles Beattie / Alex S. Evers, C. Michael Crowder / William A. Catterall, Kenneth Mackie / Eric J. Moody, Brett A. Simon, Roger A. Johns / Dennis S. Charney, S. John Mihic, R. Adron Harris / Michael F. Fleming, S. John Mihic, R. Adron Harris / Ross J. Baldessarini / Ross J. Baldessarini, Frank I. Tarazi / James O. McNamara / David G. Standaert, Anne B. Young / Howard B. Gutstein, Huda Akil / Charles P. O'Brien / Jason D. Morrow, L. Jackson Roberts II / Nancy J. Brown, L. Jackson Roberts II / Jason D. Morrow, L. Jackson Roberts II / L. Jackson Roberts II, Jason D. Morrow / Bradley J. Undem, Lawrence M. Lichtenstein / Edwin K. Jackson / Edwin K. Jackson / Edwin K. Jackson / David M. Kerins, Rose Marie Robertson, David Robertson / John A. Oates, Nancy J. Brown / Henry Ooi, Wilson Colucci / Dan M. Roden / Robert W. Mahley, Thomas P. Bersot / Willemijntje A. Hoogerwerf, Pankaj J. Pasricha / Pankaj J. Pasricha / Syed Jafri, Pankaj J. Pasricha / James W. Tracy, Leslie T. Webster, Jr. / James W. Tracy, Leslie T. Webster, Jr. / James W. Tracy, Leslie T. Webster, Jr. / James W. Tracy, Leslie T. Webster, Jr. / Henry F. Chambers / William A. Petri, Jr. / William A. Petri, Jr. / Henry F. Chambers / Henry F. Chambers / William A. Petri, Jr. / John E. Bennett / Frederick G. Hayden / Stephen P. Raffanti, David W. Haas / Paul Calabresi, Bruce A. Chabner / Bruce A. Chabner, David P. Ryan, Luis Paz-Ares / Alan M. Krensky, Terry B. Strom, Jaffrey A. Bluestone / Robert S. Hillman / Philip W. Majerus, Douglas M. Tollefsen / Keith L. Parker, Bernard P. Schimmer / Alan P. Farwell, Lewis E. Braverman / David S. Loose-Mitchell, George M. Stancel / Peter J. Snyder / Bernard P. Schimmer, Keith L. Parker / Stephan N. Davis, Daryl K. Granner / Robert Marcus / Robert Marcus, Ann M. Coulston / Robert Marcus, Ann M. Coulston / Robert Marcus, Ann M. Coulston / Eric L. Wyatt, Steven H. Sutter, Lynn A. Drake / Sayoko E. Moroi, Paul R. Lichter / Curtis D. Klaassen / Curtis D. Klaassen / Lauralea Edwards, Dan M. Roden / Kenneth E. Thummel, Danny D. Shen
0071354697
2001030728
Pharmacology
Chemotherapy
Pharmacology
Drug Therapy
RM300 / .G644 2001
QV 4 / .G6532 2001
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