Goodman and Gilman's the pharmacological basis of therapeutics

Includes bibliographical references and index

Contents Sect. I General Principles Introduction / Alfred Goodman Gilman 1 Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, and Elimination / Grant R. Wilkinson 2 Pharmacodynamics: Mechanisms of Drug Action and the Relationship Between Drug Concentration and Effect / Elliott M. Ross, Terry P. Kenakin 3 Principles of Therapeutics / Alan S. Nies 4 Principles of Toxicology and Treatment of Poisoning / Curtis D. Klaassen 5 Gene Therapy / Christopher S. Rogers, Bruce A. Sullenger, Alfred L. George, Jr. Sect. II Drugs Acting at Synaptic and Neuroeffector Junctional Sites 6 Neurotransmission: The Autonomic and Somatic Motor Nervous Systems / Brian B. Hoffman, Palmer Taylor 7 Muscarinic Receptor Agonists and Antagonists / Joan Heller Brown, Palmer Taylor 8 Anticholinesterase Agents / Palmer Taylor 9 Agents Acting at the Neuromuscular Junction and Autonomic Ganglia / Palmer Taylor 10 Catecholamines, Sympathomimetic Drugs, and Adrenergic Receptor Antagonists / Brian B. Hoffman 11 5-Hydroxytryptamine (Serotonin): Receptor Agonists and Antagonists / Elaine Sanders-Bush, Steven E. Mayer Sect. III Drugs Acting on the Central Nervous System 12 Neurotransmission and the Central Nervous System / Floyd E. Bloom 13 History and Principles of Anesthesiology / Charles Beattie 14 General Anesthetics / Alex S. Evers, C. Michael Crowder 15 Local Anesthetics / William A. Catterall, Kenneth Mackie 16 Therapeutic Gases: Oxygen, Carbon Dioxide, Nitric Oxide, and Helium / Eric J. Moody, Brett A. Simon, Roger A. Johns 17 Hypnotics and Sedatives / Dennis S. Charney, S. John Mihic, R. Adron Harris 18 Ethanol / Michael F. Fleming, S. John Mihic, R. Adron Harris 19 Drugs and the Treatment of Psychiatric Disorders: Depression and Anxiety Disorders / Ross J. Baldessarini 20 Drugs and the Treatment of Psychiatric Disorders: Psychosis and Mania / Ross J. Baldessarini, Frank I. Tarazi 21 Drugs Effective in the Therapy of the Epilepsies / James O. McNamara 22 Treatment of Central Nervous System Degenerative Disorders / David G. Standaert, Anne B. Young 23 Opioid Analgesics / Howard B. Gutstein, Huda Akil 24 Drug Addiction and Drug Abuse / Charles P. O'Brien Sect. IV Autacoids; Drug Therapy of Inflammation Introduction / Jason D. Morrow, L. Jackson Roberts II 25 Histamine, Bradykinin, and their Antagonists / Nancy J. Brown, L. Jackson Roberts II 26 Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor / Jason D. Morrow, L. Jackson Roberts II 27 Analgesic-Antipyretic and Antiinflammatory Agents and Drugs Employed in the Treatment of Gout / L. Jackson Roberts II, Jason D. Morrow 28 Drugs Used in the Treatment of Asthma / Bradley J. Undem, Lawrence M. Lichtenstein Sect. V Drugs Affecting Renal and Cardiovascular Function 29 Diuretics / Edwin K. Jackson 30 Vasopressin and Other Agents Affecting the Renal Conservation of Water / Edwin K. Jackson 31 Renin and Angiotensin / Edwin K. Jackson 32 Drugs Used for the Treatment of Myocardial Ischemia / David M. Kerins, Rose Marie Robertson, David Robertson 33 Antihypertensive Agents and the Drug Therapy of Hypertension / John A. Oates, Nancy J. Brown 34 Pharmacological Treatment of Heart Failure / Henry Ooi, Wilson Colucci 35 Antiarrhythmic Drugs / Dan M. Roden 36 Drug Therapy for Hypercholesterolemia and Dyslipidemia / Robert W. Mahley, Thomas P. Bersot Sect. VI Drugs Affecting Gastrointestinal Function 37 Agents Used for Control of Gastric Acidity and Treatment of Peptic Ulcers and Gastroesophageal Reflux Disease / Willemijntje A. Hoogerwerf, Pankaj J. Pasricha 38 Prokinetic Agents, Antiemetics, and Agents Used in Irritable Bowel Syndrome / Pankaj J. Pasricha 39 Agents Used for Diarrhea, Constipation, and Inflammatory Bowel Disease; Agents Used for Biliary and Pancreatic Disease / Syed Jafri, Pankaj J. Pasricha Sect. VII Chemotherapy of Parasitic Infections Introduction / James W. Tracy, Leslie T. Webster, Jr. 40 Drugs Used in the Chemotherapy of Protozoal Infections: Malaria / James W. Tracy, Leslie T. Webster, Jr. 41 Drugs Used in the Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections / James W. Tracy, Leslie T. Webster, Jr. 42 Drugs Used in the Chemotherapy of Helminthiasis / James W. Tracy, Leslie T. Webster, Jr. Sect. VIII Chemotherapy of Microbial Diseases 43 Antimicrobial Agents: General Considerations / Henry F. Chambers 44 Antimicrobial Agents: Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections / William A. Petri, Jr. 45 Antimicrobial Agents: Penicillins, Cephalosporins, and Other [beta]-Lactam Antibiotics / William A. Petri, Jr. 46 Antimicrobial Agents: The Aminoglycosides / Henry F. Chambers 47 Antimicrobial Agents: Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents / Henry F. Chambers 48 Antimicrobial Agents: Drugs Used in the Chemotherapy of Tuberculosis, Mycobacterium avium Complex Disease, and Leprosy / William A. Petri, Jr. 49 Antimicrobial Agents: Antifungal Agents / John E. Bennett 50 Antimicrobial Agents: Antiviral Agents (Nonretroviral) / Frederick G. Hayden 51 Antimicrobial Agents: Antiretroviral Agents / Stephen P. Raffanti, David W. Haas Sect. IX Chemotherapy of Neoplastic Diseases Introduction / Paul Calabresi, Bruce A. Chabner 52 Antineoplastic Agents [and others] / Bruce A. Chabner, David P. Ryan, Luis Paz-Ares Sect. X Drugs Used for Immunomodulation 53 Immunomodulators: Immunosuppressive Agents, Tolerogens, and Immunostimulants / Alan M. Krensky, Terry B. Strom, Jaffrey A. Bluestone Sect. XI Drugs Acting on the Blood and the Blood-Forming Organs 54 Hematopoietic Agents: Growth Factors, Minerals, and Vitamins / Robert S. Hillman 55 Anticoagulant, Thrombolytic, and Antiplatelet Drugs / Philip W. Majerus, Douglas M. Tollefsen Sect. XII Hormones and Hormone Antagonists 56 Pituitary Hormones and Their Hypothalamic Releasing Factors / Keith L. Parker, Bernard P. Schimmer 57 Thyroid and Antithyroid Drugs / Alan P. Farwell, Lewis E. Braverman 58 Estrogens and Progestins / David S. Loose-Mitchell, George M. Stancel 59 Androgens / Peter J. Snyder 60 Adrenocorticotropic Hormone; Adrenocortical Steroids and Their Synthetic Analogs; Inhibitors of the Synthesis and Actions of Adrenocortical Hormones / Bernard P. Schimmer, Keith L. Parker 61 Insulin, Oral Hypoglycemic Agents, and the Pharmacology of the Endocrine Pancreas / Stephan N. Davis, Daryl K. Granner 62 Agents Affecting Calcification and Bone Turnover: Calcium, Phosphate, Parathyroid Hormone, Vitamin D, Calcitonin, and Other Compounds / Robert Marcus Sect. XIII The Vitamins Introduction / Robert Marcus, Ann M. Coulston 63 Water-Soluble Vitamins: The Vitamin B Complex and Ascorbic Acid / Robert Marcus, Ann M. Coulston 64 Fat-Soluble Vitamins: Vitamins A, K, and E / Robert Marcus, Ann M. Coulston Sect. XIV Dermatology 65 Dermatological Pharmacology / Eric L. Wyatt, Steven H. Sutter, Lynn A. Drake Sect. XV Ophthalmology 66 Ocular Pharmacology / Sayoko E. Moroi, Paul R. Lichter Sect. XVI Toxicology 67 Heavy Metals and Heavy-Metals Antagonists / Curtis D. Klaassen 68 Nonmetallic Environmental Toxicants: Air Pollutants, Solvents and Vapors, and Pesticides / Curtis D. Klaassen App. I Principles of Prescription Order Writing and Patient Compliance / Lauralea Edwards, Dan M. Roden App. II Design and Optimization of Dosage Regimens: Pharmacokinetic Data / Kenneth E. Thummel, Danny D. Shen Index